Therefore, no exact percentages for the individual side effects ⦠In the past I have used the over-the-counter drug Sudaphed to counteract the tri-mix after ejaculation thus relaxing the erection and reducing the ache. Phenylephrine doesn't last as long as other decongestants like pseudoephedrine (Sudafed). Sudaphed is no longer available without a prescription and I would like to know if there is another OTC drug which would have the same relaxing effects ⦠Learn more about Sudafed PE ⦠Drugs.com. Cardiovascular Effects Of Sudafed. Visit cvs.com ⦠Sudafed Pe (Phenylephrine) is a good medication for relieving stuffy nose. The mild ones will die down once the body gets adjusted to the drug. However, if the intensity of any of these side effects ⦠Get emergency medical help if you have signs of an allergic reaction: ⦠You may report side effects ⦠The side effects of Sudafed can be classified into mild and severe. It doesn't work as well as pseudoephedrine (Sudafed), but it has fewer side effects. Sudafed PE is a non-prescription medication, and detailed information about possible side effects is not provided in the labeling for non-prescription medications. Each pill contains 10 milligrams of phenylephrine HCl. Pseudoephedrine is also called by the brand names Sudafed ⦠Sudafed ⦠Sudafed PE Congestion Oral tablet drug summary. Our Sudafed Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Find everything you need to know about Sudafed PE Sinus & Allergy, including what it is used for, warnings, reviews, side effects, and interactions. This is not a complete list of side effects and others may occur. (2012, September). Phenylephrine is ⦠Sudafed PE products donât ⦠Call your doctor for medical advice about side effects. It might also make you feel restless, nervous or shaky. Find medication information including related drug classes, side effects, patient statistics and answers to frequently asked questions. Common side effects include feeling sick, headaches, a dry mouth, a fast or irregular heartbeat, or increased blood pressure. Sudafed PE Cold & Cough Side Effects. Sudafed PE pills are round, red, film-coated, and embossed with "44453" on one side. Sudafed (pseudoephedrine) is an alpha agonist used to treat nasal congestion and sinus pressure.It works by restricting the blood vessels in the nose and sinuses. Any additional side effects, interactions, or warnings caused by naproxen sodium are not covered in this article. The active ingredient in Sudafed, pseudoephedrine, can increase blood pressure due to its vasoconstrictive effects⦠Side Effects What are the side effects of Phenylephrine (Sudafed PE)?.